Package takes frequencies of mutations as reported by high throughput sequencing data from cancer and fits a theoretical neutral model of tumour evolution. Package outputs summary statistics and contains code for plotting the data and model fits. See Williams et al 2016 <doi:10.1038/ng.3489> and Williams et al 2017 <doi:10.1101/096305> for further details of the method.
| Version: | 0.0.3 |
| Depends: | R (≥ 3.4) |
| Imports: | dplyr, ggplot2, scales, pracma, ggpmisc, cowplot |
| Suggests: | knitr, rmarkdown, testthat |
| Published: | 2021-02-16 |
| DOI: | 10.32614/CRAN.package.neutralitytestr |
| Author: | Marc Williams [aut, cre] |
| Maintainer: | Marc Williams <marcjwilliams1 at gmail.com> |
| BugReports: | https://github.com/marcjwilliams1/neutralitytestr/issues |
| License: | MIT + file LICENSE |
| URL: | https://github.com/marcjwilliams1/neutralitytestr |
| NeedsCompilation: | no |
| Materials: | README NEWS |
| CRAN checks: | neutralitytestr results |
| Reference manual: | neutralitytestr.pdf |
| Vignettes: |
neutralitytestr: Testing a neutral evolutionary model on cancer sequencing data |
| Package source: | neutralitytestr_0.0.3.tar.gz |
| Windows binaries: | r-devel: neutralitytestr_0.0.3.zip, r-release: neutralitytestr_0.0.3.zip, r-oldrel: neutralitytestr_0.0.3.zip |
| macOS binaries: | r-release (arm64): neutralitytestr_0.0.3.tgz, r-oldrel (arm64): neutralitytestr_0.0.3.tgz, r-release (x86_64): neutralitytestr_0.0.3.tgz, r-oldrel (x86_64): neutralitytestr_0.0.3.tgz |
| Old sources: | neutralitytestr archive |
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